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Analyzing of Alzheimer’s Disease Based on Biomedical and Socio-Economic Approach Using Molecular Communication, Artificial Neural Network, and Random Forest Models

  • Yuksel Bayraktar
  • , Esme Isik
  • , Ibrahim Isik
  • , Ayfer Ozyilmaz
  • , Metin Toprak
  • , Fatma Kahraman Guloglu
  • , Serdar Aydin*
  • *Corresponding author for this work
  • Istanbul University
  • Malatya Turgut Ozal University
  • Inonu University
  • Kocaeli University
  • Istanbul Sabahattin Zaim University
  • Yalova University
  • Southern Illinois University

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Alzheimer’s disease will affect more people with increases in the elderly population, as the elderly population of countries everywhere generally rises significantly. However, other factors such as regional climates, environmental conditions and even eating and drinking habits may trigger Alzheimer’s disease or affect the life quality of individuals already suffering from this disease. Today, the subject of biomedical engineering is being studied intensively by many researchers considering that it has the potential to produce solutions to various diseases such as Alzheimer’s caused by problems in molecule or cell communication. In this study, firstly, a molecular communication model with the potential to be used in the treatment and/or diagnosis of Alzheimer’s disease was proposed, and its results were analyzed with an artificial neural network model. Secondly, the ratio of people suffering from Alzheimer’s disease to the total population, along with data of educational status, income inequality, poverty threshold, and the number of the poor in Turkey were subjected to detailed distribution analysis by using the random forest model statistically. As a result of the study, it was determined that a higher income level was causally associated with a lower risk of Alzheimer’s disease.

Original languageEnglish
Article number7901
JournalSustainability (Switzerland)
Volume14
Issue number13
DOIs
Publication statusPublished - 1 Jul 2022
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 10 - Reduced Inequalities
    SDG 10 Reduced Inequalities

OECD Field of Science

  • 1.6 Biological Sciences
  • 1.2 Computer and Information Sciences
  • 3.1 Basic Medicine

Keywords

  • Alzheimer’s disease
  • Turkey
  • amyloid beta
  • income inequality
  • molecular communication
  • neural network
  • number of received molecules
  • random forest
  • socioeconomic
  • total population

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