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Antigeny sistemy HLA pri iuvenil'nom revmatoidnom artrite.

Translated title of the contribution: HLA antigens in juvenile rheumatoid arthritis
  • I. V. Rumba*
  • , A. M. Sochnev
  • , E. M. Kukaǐne
  • , A. M. Burshteǐn
  • , L. I. Benevolenskaia
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Antigens of I class HLA system (locus A and B) were investigated in 67 patients of Latvian nationality suffering from juvenile rheumatoid arthritis (JRA). Associations of HLA antigens with juvenile rheumatoid arthritis partially coincided with the ones revealed earlier. Typing established an increased incidence of antigen B27 (p less than 0.01) and gaplotype A2, B40 (p less than 0.01). Antigen B15 possessed a protective action with respect to JRA. Interlocus combinations demonstrated a closer association with the disease than a single antigen. The authors also revealed markers of various clinico-anatomical variants of JRA.

Translated title of the contributionHLA antigens in juvenile rheumatoid arthritis
Original languageRussian
Pages (from-to)23-27
Number of pages5
JournalRevmatologia
Issue number3
Publication statusPublished - Jul 1990

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