Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites

Dmitrijs Zablockis; Izolda Segal; Alla Zablotskaya; Mihails Majorovs; Tuan Anh Nguyen

doi:10.1016/B978-0-12-823688-8.00013-2

Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites

Dmitrijs Zablockis
, Izolda Segal
, Alla Zablotskaya
, Mihails Majorovs
, Tuan Anh Nguyen

Synthermion LLC
Latvian Institute of Organic Synthesis
Vietnamese Academy of Science and Technology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

4 Citations (Scopus)

Abstract

Magnetic nanoparticles are considered the next generation of antimicrobial agents, having the benefits of magnetic guidance, making them potentially useful for therapeutic and diagnostic applications. Hybridization of inorganic-organic functionalities has emerged as an efficient way to achieve advanced therapeutic goals. We present a brief overview of the popular strategies and the recurrent functional themes in designing antimicrobial magnetic nanosystems. The effect of functionalization and combining nanosystems engineering with drug discovery workflow to increase the inhibitory potential of magnetic nanocomposites against infectious pathogens is discussed. The integration of inorganic-organic functionalities based on a magnetic core has high capacity to avoid the microbial defense mechanisms and eliminate resistant strains.

Original language	English
Title of host publication	Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications
Place of Publication	[S.l.]
Publisher	Woodhead Publishing
Pages	501-527
ISBN (Print)	9780128236888
DOIs	https://doi.org/10.1016/B978-0-12-823688-8.00013-2
Publication status	Published - 2021

Publication series

Name	Woodhead Publishing series in electronic and optical materials

Keywords

Antimicrobial activity
Cytotoxicity
Drug delivery
Magnetic field
Quarternary ammonium compounds
Self-assembly
Superparamagnetic iron oxide nanoparticles
Surface functionalization

OECD Field of Science

1.3 Physical Sciences

Access to Document

10.1016/B978-0-12-823688-8.00013-2

Cite this

Zablockis, D., Segal, I., Zablotskaya, A., Majorovs, M., & Nguyen, T. A. (2021). Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites. In Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications (pp. 501-527). (Woodhead Publishing series in electronic and optical materials). Woodhead Publishing. https://doi.org/10.1016/B978-0-12-823688-8.00013-2

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abstract = "Magnetic nanoparticles are considered the next generation of antimicrobial agents, having the benefits of magnetic guidance, making them potentially useful for therapeutic and diagnostic applications. Hybridization of inorganic-organic functionalities has emerged as an efficient way to achieve advanced therapeutic goals. We present a brief overview of the popular strategies and the recurrent functional themes in designing antimicrobial magnetic nanosystems. The effect of functionalization and combining nanosystems engineering with drug discovery workflow to increase the inhibitory potential of magnetic nanocomposites against infectious pathogens is discussed. The integration of inorganic-organic functionalities based on a magnetic core has high capacity to avoid the microbial defense mechanisms and eliminate resistant strains.",

keywords = "Antimicrobial activity, Cytotoxicity, Drug delivery, Magnetic field, Quarternary ammonium compounds, Self-assembly, Superparamagnetic iron oxide nanoparticles, Surface functionalization",

author = "Dmitrijs Zablockis and Izolda Segal and Alla Zablotskaya and Mihails Majorovs and Nguyen, \{Tuan Anh\}",

year = "2021",

doi = "10.1016/B978-0-12-823688-8.00013-2",

language = "English",

isbn = "9780128236888",

series = "Woodhead Publishing series in electronic and optical materials",

publisher = "Woodhead Publishing",

pages = "501--527",

booktitle = "Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications",

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Zablockis, D, Segal, I, Zablotskaya, A, Majorovs, M & Nguyen, TA 2021, Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites. in Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications. Woodhead Publishing series in electronic and optical materials, Woodhead Publishing, [S.l.], pp. 501-527. https://doi.org/10.1016/B978-0-12-823688-8.00013-2

Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites. / Zablockis, Dmitrijs; Segal, Izolda; Zablotskaya, Alla et al.
Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications. [S.l.]: Woodhead Publishing, 2021. p. 501-527 (Woodhead Publishing series in electronic and optical materials).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

TY - CHAP

T1 - Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites

AU - Zablockis, Dmitrijs

AU - Segal, Izolda

AU - Zablotskaya, Alla

AU - Majorovs, Mihails

AU - Nguyen, Tuan Anh

PY - 2021

Y1 - 2021

N2 - Magnetic nanoparticles are considered the next generation of antimicrobial agents, having the benefits of magnetic guidance, making them potentially useful for therapeutic and diagnostic applications. Hybridization of inorganic-organic functionalities has emerged as an efficient way to achieve advanced therapeutic goals. We present a brief overview of the popular strategies and the recurrent functional themes in designing antimicrobial magnetic nanosystems. The effect of functionalization and combining nanosystems engineering with drug discovery workflow to increase the inhibitory potential of magnetic nanocomposites against infectious pathogens is discussed. The integration of inorganic-organic functionalities based on a magnetic core has high capacity to avoid the microbial defense mechanisms and eliminate resistant strains.

AB - Magnetic nanoparticles are considered the next generation of antimicrobial agents, having the benefits of magnetic guidance, making them potentially useful for therapeutic and diagnostic applications. Hybridization of inorganic-organic functionalities has emerged as an efficient way to achieve advanced therapeutic goals. We present a brief overview of the popular strategies and the recurrent functional themes in designing antimicrobial magnetic nanosystems. The effect of functionalization and combining nanosystems engineering with drug discovery workflow to increase the inhibitory potential of magnetic nanocomposites against infectious pathogens is discussed. The integration of inorganic-organic functionalities based on a magnetic core has high capacity to avoid the microbial defense mechanisms and eliminate resistant strains.

KW - Antimicrobial activity

KW - Cytotoxicity

KW - Drug delivery

KW - Magnetic field

KW - Quarternary ammonium compounds

KW - Self-assembly

KW - Superparamagnetic iron oxide nanoparticles

KW - Surface functionalization

UR - https://www.sciencedirect.com/science/article/pii/B9780128236888000132

U2 - 10.1016/B978-0-12-823688-8.00013-2

DO - 10.1016/B978-0-12-823688-8.00013-2

M3 - Chapter

SN - 9780128236888

T3 - Woodhead Publishing series in electronic and optical materials

SP - 501

EP - 527

BT - Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications

PB - Woodhead Publishing

CY - [S.l.]

ER -

Zablockis D, Segal I, Zablotskaya A, Majorovs M, Nguyen TA. Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites. In Magnetic Nanoparticle Based Hybrid Materials Fundamentals and Applications. [S.l.]: Woodhead Publishing. 2021. p. 501-527. (Woodhead Publishing series in electronic and optical materials). doi: 10.1016/B978-0-12-823688-8.00013-2

Antimicrobial activity of hybrid organic-inorganic core-shell magnetic nanocomposites

Abstract

Publication series

Keywords

OECD Field of Science

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