Biologically active conformation of tuftsin

G. V. Nikiforovich; I. T. Liepina; I. P. Sekacis; E. E. Liepins; B. S. Katayev; N. I. Veretennikova; G. I. Chipens

doi:10.1111/j.1399-3011.1984.tb02719.x

Biologically active conformation of tuftsin

G. V. Nikiforovich^*
, I. T. Liepina
, I. P. Sekacis
, E. E. Liepins
, B. S. Katayev
, N. I. Veretennikova
, G. I. Chipens

^*Corresponding author for this work

Latvian Academy of Sciences

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The main features of the assumed biologically active conformation of the tuftsin molecule have been described using the energy calculations as well as the n.m.r. and CD‐spectroscopy measurements performed for the conformationally rigid active cycloanalogue, Thr‐L‐ys‐Pro‐Arg. The biologically active conformation has been shown to be of BBRB or BLRB backbone type with the trans‐conformation of proline residue.

Original language	English
Pages (from-to)	271-275
Number of pages	5
Journal	International Journal of Peptide and Protein Research
Volume	23
Issue number	3
DOIs	https://doi.org/10.1111/j.1399-3011.1984.tb02719.x
Publication status	Published - Mar 1984
Externally published	Yes

Keywords

biologically active conformation
cycloanalogues
energy calculations
tuftsin

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10.1111/j.1399-3011.1984.tb02719.x

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title = "Biologically active conformation of tuftsin",

abstract = "The main features of the assumed biologically active conformation of the tuftsin molecule have been described using the energy calculations as well as the n.m.r. and CD‐spectroscopy measurements performed for the conformationally rigid active cycloanalogue, Thr‐L‐ys‐Pro‐Arg. The biologically active conformation has been shown to be of BBRB or BLRB backbone type with the trans‐conformation of proline residue.",

keywords = "biologically active conformation, cycloanalogues, energy calculations, tuftsin",

author = "Nikiforovich, \{G. V.\} and Liepina, \{I. T.\} and Sekacis, \{I. P.\} and Liepins, \{E. E.\} and Katayev, \{B. S.\} and Veretennikova, \{N. I.\} and Chipens, \{G. I.\}",

year = "1984",

month = mar,

doi = "10.1111/j.1399-3011.1984.tb02719.x",

language = "English",

volume = "23",

pages = "271--275",

journal = "International Journal of Peptide and Protein Research",

issn = "0367-8377",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "3",

}

TY - JOUR

T1 - Biologically active conformation of tuftsin

AU - Nikiforovich, G. V.

AU - Liepina, I. T.

AU - Sekacis, I. P.

AU - Liepins, E. E.

AU - Katayev, B. S.

AU - Veretennikova, N. I.

AU - Chipens, G. I.

PY - 1984/3

Y1 - 1984/3

N2 - The main features of the assumed biologically active conformation of the tuftsin molecule have been described using the energy calculations as well as the n.m.r. and CD‐spectroscopy measurements performed for the conformationally rigid active cycloanalogue, Thr‐L‐ys‐Pro‐Arg. The biologically active conformation has been shown to be of BBRB or BLRB backbone type with the trans‐conformation of proline residue.

AB - The main features of the assumed biologically active conformation of the tuftsin molecule have been described using the energy calculations as well as the n.m.r. and CD‐spectroscopy measurements performed for the conformationally rigid active cycloanalogue, Thr‐L‐ys‐Pro‐Arg. The biologically active conformation has been shown to be of BBRB or BLRB backbone type with the trans‐conformation of proline residue.

KW - biologically active conformation

KW - cycloanalogues

KW - energy calculations

KW - tuftsin

UR - https://www.scopus.com/pages/publications/0021326626

U2 - 10.1111/j.1399-3011.1984.tb02719.x

DO - 10.1111/j.1399-3011.1984.tb02719.x

M3 - Article

AN - SCOPUS:0021326626

SN - 0367-8377

VL - 23

SP - 271

EP - 275

JO - International Journal of Peptide and Protein Research

JF - International Journal of Peptide and Protein Research

IS - 3

ER -

Biologically active conformation of tuftsin

Abstract

Keywords

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