Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Vera Rudzite; Edite Jurika; Uldis Kalnins; Andrejs Erglis; Karlis Trusinskis; Sanda Jegere; Barbara Frick; Dietmar Fuchs

doi:10.1515/pteridines.2002.13.3.100

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Vera Rudzite^*
, Edite Jurika
, Uldis Kalnins
, Andrejs Erglis
, Karlis Trusinskis
, Sanda Jegere
, Barbara Frick
, Dietmar Fuchs

^*Corresponding author for this work

University of Latvia

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography. Patients have been observed before percutaneus transluminal coronary angioplasty (31 patients with one-artery disease, 30 with two- or three-artery disease, 26 with restenosis). Results suggest that lowered serum pyridoxal-5-phosphate concentrations were an earlier indicator of coronary heart disease than increase of serum homocysteine concentration above 15 μmol/L. An increase of serum neopterin concentration appears to be a marker of coronary disease activity rather than a marker of the presence of coronary heart disease.

Original language	English
Pages (from-to)	100-103
Number of pages	4
Journal	Pteridines
Volume	13
Issue number	3
DOIs	https://doi.org/10.1515/pteridines.2002.13.3.100
Publication status	Published - Sept 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Coronary heart disease
Homocysteine
Neopterin
Pyridoxal-5-phosphate

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10.1515/pteridines.2002.13.3.100

Cite this

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title = "Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease",

abstract = "Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography. Patients have been observed before percutaneus transluminal coronary angioplasty (31 patients with one-artery disease, 30 with two- or three-artery disease, 26 with restenosis). Results suggest that lowered serum pyridoxal-5-phosphate concentrations were an earlier indicator of coronary heart disease than increase of serum homocysteine concentration above 15 μmol/L. An increase of serum neopterin concentration appears to be a marker of coronary disease activity rather than a marker of the presence of coronary heart disease.",

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author = "Vera Rudzite and Edite Jurika and Uldis Kalnins and Andrejs Erglis and Karlis Trusinskis and Sanda Jegere and Barbara Frick and Dietmar Fuchs",

year = "2002",

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doi = "10.1515/pteridines.2002.13.3.100",

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TY - JOUR

T1 - Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

AU - Rudzite, Vera

AU - Jurika, Edite

AU - Kalnins, Uldis

AU - Erglis, Andrejs

AU - Trusinskis, Karlis

AU - Jegere, Sanda

AU - Frick, Barbara

AU - Fuchs, Dietmar

PY - 2002/9

Y1 - 2002/9

N2 - Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography. Patients have been observed before percutaneus transluminal coronary angioplasty (31 patients with one-artery disease, 30 with two- or three-artery disease, 26 with restenosis). Results suggest that lowered serum pyridoxal-5-phosphate concentrations were an earlier indicator of coronary heart disease than increase of serum homocysteine concentration above 15 μmol/L. An increase of serum neopterin concentration appears to be a marker of coronary disease activity rather than a marker of the presence of coronary heart disease.

AB - Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography. Patients have been observed before percutaneus transluminal coronary angioplasty (31 patients with one-artery disease, 30 with two- or three-artery disease, 26 with restenosis). Results suggest that lowered serum pyridoxal-5-phosphate concentrations were an earlier indicator of coronary heart disease than increase of serum homocysteine concentration above 15 μmol/L. An increase of serum neopterin concentration appears to be a marker of coronary disease activity rather than a marker of the presence of coronary heart disease.

KW - Coronary heart disease

KW - Homocysteine

KW - Neopterin

KW - Pyridoxal-5-phosphate

UR - https://www.scopus.com/pages/publications/0036744620

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DO - 10.1515/pteridines.2002.13.3.100

M3 - Article

AN - SCOPUS:0036744620

SN - 0933-4807

VL - 13

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JO - Pteridines

JF - Pteridines

IS - 3

ER -

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Abstract

UN SDGs

Keywords

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