Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)

Jelena Jotanovic; Henning Bünsow Boldt; Mark Burton; Marianne Skovsager Andersen; Daniel Bengtsson; Thomas Olsson Bontell; Bertil Ekman; Britt Edén Engström; Ulla Feldt-Rasmussen; Ansgar Heck; Antonia Jakovcevic; Jens Otto L. Jørgensen; Ivana Kraljevic; Jacek Kunicki; John R. Lindsay; Marco Losa; Paul Benjamin Loughrey; Dominique Maiter; Maria Maksymowicz; Emilija Manojlovic-Gacic; Jens Pahnke; Stephan Petersenn; Maria Petersson; Vera Popovic; Oskar Ragnarsson; Åse Krogh Rasmussen; Zita Reisz; Wolfgang Saeger; Camilla Schalin-Jäntti; David Scheie; Maria Rosa Terreni; Olli Tynninen; Ben Whitelaw; Pia Burman; Olivera Casar-Borota

doi:10.1007/s00401-024-02838-3

Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)

Jelena Jotanovic
, Henning Bünsow Boldt
, Mark Burton
, Marianne Skovsager Andersen
, Daniel Bengtsson
, Thomas Olsson Bontell
, Bertil Ekman
, Britt Edén Engström
, Ulla Feldt-Rasmussen
, Ansgar Heck
, Antonia Jakovcevic
, Jens Otto L. Jørgensen
, Ivana Kraljevic
, Jacek Kunicki
, John R. Lindsay
, Marco Losa
, Paul Benjamin Loughrey
, Dominique Maiter
, Maria Maksymowicz
, Emilija Manojlovic-Gacic

Jens Pahnke, Stephan Petersenn, Maria Petersson, Vera Popovic, Oskar Ragnarsson, Åse Krogh Rasmussen, Zita Reisz, Wolfgang Saeger, Camilla Schalin-Jäntti, David Scheie, Maria Rosa Terreni, Olli Tynninen, Ben Whitelaw, Pia Burman, Olivera Casar-Borota^*

^*Corresponding author for this work

Uppsala University
University of Southern Denmark
Linköping University
Kalmar County Hospital
University of Gothenburg
Sahlgrenska University Hospital
University of Copenhagen
University of Oslo
University of Zagreb
Aarhus University
Maria Sklodowska-Curie Institute of Oncology
Royal Victoria Hospital Belfast
Vita-Salute San Raffaele University
Queen's University Belfast
Université catholique de Louvain
University of Belgrade
ENDOC Center for Endocrine Tumors
University of Duisburg-Essen
Karolinska Institutet
King’s College Hospital
University of Hamburg
Helsinki University Central Hospital
University of Helsinki
Lund University

Research output: Contribution to journal › Comment/debate/note

Abstract

In the original publication of this article, upper and lower part of Table 2 was incorrectly formatted. The incorrect and correct version of Table 2 are shown in this correction article. The original article has been corrected. Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper table) and in the entire cohort (lower table) Hypermethylated and positive enriched in PC pval padj NES size KEGG cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG focal adhesion 7.16E-05 0.0015 1.44 191 KEGG adherens junction 8.97E-05 0.0017 1.64 67 KEGG calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG gap junction 0.0063 0.036 1.40 83 KEGG axon guidance 1.60E-06 0.00028 1.53 122 KEGG calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG leukocyte transendothelial migration 0.011 0.10 1.28 108 Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper part of the table) and in the entire cohort (lower part of the table) Hypermethylated and positive enriched in PC pval padj NES size KEGG Cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG Axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG Pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG Neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG Focal adhesion 7.16E-05 0.0015 1.44 191 KEGG Adherens junction 8.97E-05 0.0017 1.64 67 KEGG Calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG Leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG Gap junction 0.0063 0.036 1.40 83 Hypermethylated and positive enriched in PC pval padj NES size KEGG Axon guidance 1.60E-06 0.00028 1.53 122 KEGG Calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG Neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG Regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG Cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG Leukocyte transendothelial migration 0.011 0.10 1.28

Original language	English
Article number	4
Journal	Acta Neuropathologica
Volume	149
Issue number	1
DOIs	https://doi.org/10.1007/s00401-024-02838-3
Publication status	Published - Jun 2025
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/s00401-024-02838-3

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Jotanovic, J., Boldt, H. B., Burton, M., Andersen, M. S., Bengtsson, D., Bontell, T. O., Ekman, B., Engström, B. E., Feldt-Rasmussen, U., Heck, A., Jakovcevic, A., Jørgensen, J. O. L., Kraljevic, I., Kunicki, J., Lindsay, J. R., Losa, M., Loughrey, P. B., Maiter, D., Maksymowicz, M., ... Casar-Borota, O. (2025). Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5). Acta Neuropathologica, 149(1), Article 4. https://doi.org/10.1007/s00401-024-02838-3

@article{b1b9fa58c62841d1a1f66654bd3386ff,

title = "Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)",

abstract = "In the original publication of this article, upper and lower part of Table 2 was incorrectly formatted. The incorrect and correct version of Table 2 are shown in this correction article. The original article has been corrected. Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper table) and in the entire cohort (lower table) Hypermethylated and positive enriched in PC pval padj NES size KEGG cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG focal adhesion 7.16E-05 0.0015 1.44 191 KEGG adherens junction 8.97E-05 0.0017 1.64 67 KEGG calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG gap junction 0.0063 0.036 1.40 83 KEGG axon guidance 1.60E-06 0.00028 1.53 122 KEGG calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG leukocyte transendothelial migration 0.011 0.10 1.28 108 Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper part of the table) and in the entire cohort (lower part of the table) Hypermethylated and positive enriched in PC pval padj NES size KEGG Cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG Axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG Pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG Neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG Focal adhesion 7.16E-05 0.0015 1.44 191 KEGG Adherens junction 8.97E-05 0.0017 1.64 67 KEGG Calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG Leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG Gap junction 0.0063 0.036 1.40 83 Hypermethylated and positive enriched in PC pval padj NES size KEGG Axon guidance 1.60E-06 0.00028 1.53 122 KEGG Calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG Neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG Regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG Cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG Leukocyte transendothelial migration 0.011 0.10 1.28",

author = "Jelena Jotanovic and Boldt, \{Henning B{\"u}nsow\} and Mark Burton and Andersen, \{Marianne Skovsager\} and Daniel Bengtsson and Bontell, \{Thomas Olsson\} and Bertil Ekman and Engstr{\"o}m, \{Britt Ed{\'e}n\} and Ulla Feldt-Rasmussen and Ansgar Heck and Antonia Jakovcevic and J{\o}rgensen, \{Jens Otto L.\} and Ivana Kraljevic and Jacek Kunicki and Lindsay, \{John R.\} and Marco Losa and Loughrey, \{Paul Benjamin\} and Dominique Maiter and Maria Maksymowicz and Emilija Manojlovic-Gacic and Jens Pahnke and Stephan Petersenn and Maria Petersson and Vera Popovic and Oskar Ragnarsson and Rasmussen, \{{\AA}se Krogh\} and Zita Reisz and Wolfgang Saeger and Camilla Schalin-J{\"a}ntti and David Scheie and Terreni, \{Maria Rosa\} and Olli Tynninen and Ben Whitelaw and Pia Burman and Olivera Casar-Borota",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2025",

month = jun,

doi = "10.1007/s00401-024-02838-3",

language = "English",

volume = "149",

journal = "Acta Neuropathologica",

issn = "0001-6322",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "1",

}

Jotanovic, J, Boldt, HB, Burton, M, Andersen, MS, Bengtsson, D, Bontell, TO, Ekman, B, Engström, BE, Feldt-Rasmussen, U, Heck, A, Jakovcevic, A, Jørgensen, JOL, Kraljevic, I, Kunicki, J, Lindsay, JR, Losa, M, Loughrey, PB, Maiter, D, Maksymowicz, M, Manojlovic-Gacic, E, Pahnke, J, Petersenn, S, Petersson, M, Popovic, V, Ragnarsson, O, Rasmussen, ÅK, Reisz, Z, Saeger, W, Schalin-Jäntti, C, Scheie, D, Terreni, MR, Tynninen, O, Whitelaw, B, Burman, P & Casar-Borota, O 2025, 'Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)', Acta Neuropathologica, vol. 149, no. 1, 4. https://doi.org/10.1007/s00401-024-02838-3

Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5). / Jotanovic, Jelena; Boldt, Henning Bünsow; Burton, Mark et al.
In: Acta Neuropathologica, Vol. 149, No. 1, 4, 06.2025.

Research output: Contribution to journal › Comment/debate/note

TY - JOUR

T1 - Correction to

T2 - Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)

AU - Jotanovic, Jelena

AU - Boldt, Henning Bünsow

AU - Burton, Mark

AU - Andersen, Marianne Skovsager

AU - Bengtsson, Daniel

AU - Bontell, Thomas Olsson

AU - Ekman, Bertil

AU - Engström, Britt Edén

AU - Feldt-Rasmussen, Ulla

AU - Heck, Ansgar

AU - Jakovcevic, Antonia

AU - Jørgensen, Jens Otto L.

AU - Kraljevic, Ivana

AU - Kunicki, Jacek

AU - Lindsay, John R.

AU - Losa, Marco

AU - Loughrey, Paul Benjamin

AU - Maiter, Dominique

AU - Maksymowicz, Maria

AU - Manojlovic-Gacic, Emilija

AU - Pahnke, Jens

AU - Petersenn, Stephan

AU - Petersson, Maria

AU - Popovic, Vera

AU - Ragnarsson, Oskar

AU - Rasmussen, Åse Krogh

AU - Reisz, Zita

AU - Saeger, Wolfgang

AU - Schalin-Jäntti, Camilla

AU - Scheie, David

AU - Terreni, Maria Rosa

AU - Tynninen, Olli

AU - Whitelaw, Ben

AU - Burman, Pia

AU - Casar-Borota, Olivera

PY - 2025/6

Y1 - 2025/6

N2 - In the original publication of this article, upper and lower part of Table 2 was incorrectly formatted. The incorrect and correct version of Table 2 are shown in this correction article. The original article has been corrected. Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper table) and in the entire cohort (lower table) Hypermethylated and positive enriched in PC pval padj NES size KEGG cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG focal adhesion 7.16E-05 0.0015 1.44 191 KEGG adherens junction 8.97E-05 0.0017 1.64 67 KEGG calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG gap junction 0.0063 0.036 1.40 83 KEGG axon guidance 1.60E-06 0.00028 1.53 122 KEGG calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG leukocyte transendothelial migration 0.011 0.10 1.28 108 Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper part of the table) and in the entire cohort (lower part of the table) Hypermethylated and positive enriched in PC pval padj NES size KEGG Cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG Axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG Pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG Neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG Focal adhesion 7.16E-05 0.0015 1.44 191 KEGG Adherens junction 8.97E-05 0.0017 1.64 67 KEGG Calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG Leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG Gap junction 0.0063 0.036 1.40 83 Hypermethylated and positive enriched in PC pval padj NES size KEGG Axon guidance 1.60E-06 0.00028 1.53 122 KEGG Calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG Neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG Regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG Cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG Leukocyte transendothelial migration 0.011 0.10 1.28

AB - In the original publication of this article, upper and lower part of Table 2 was incorrectly formatted. The incorrect and correct version of Table 2 are shown in this correction article. The original article has been corrected. Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper table) and in the entire cohort (lower table) Hypermethylated and positive enriched in PC pval padj NES size KEGG cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG focal adhesion 7.16E-05 0.0015 1.44 191 KEGG adherens junction 8.97E-05 0.0017 1.64 67 KEGG calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG gap junction 0.0063 0.036 1.40 83 KEGG axon guidance 1.60E-06 0.00028 1.53 122 KEGG calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG leukocyte transendothelial migration 0.011 0.10 1.28 108 Relevant significantly enriched gene sets associated with the DMPs that differed between aggressive and metastatic PitNETs in the first surgery specimens (upper part of the table) and in the entire cohort (lower part of the table) Hypermethylated and positive enriched in PC pval padj NES size KEGG Cell adhesion molecules CAMS 6.26E-07 5.63E-05 1.65 122 KEGG Axon guidance 6.51E-07 5.63E-05 1.65 122 KEGG Pathways in cancer 1.43E-06 8.24E-05 1.44 313 KEGG Neuroactive ligand receptor interaction 6.39E-06 0.00028 1.44 249 KEGG Focal adhesion 7.16E-05 0.0015 1.44 191 KEGG Adherens junction 8.97E-05 0.0017 1.64 67 KEGG Calcium signaling pathway 0.00025 0.0039 1.40 166 KEGG Leukocyte transendothelial migration 0.0019 0.019 1.43 108 KEGG ECM receptor interaction 0.0019 0.019 1.49 83 KEGG Gap junction 0.0063 0.036 1.40 83 Hypermethylated and positive enriched in PC pval padj NES size KEGG Axon guidance 1.60E-06 0.00028 1.53 122 KEGG Calcium signaling pathway 3.22E-06 0.00028 1.44 166 KEGG Neuroactive ligand receptor interaction 0.00010 0.0045 1.31 249 KEGG Regulation of actin cytoskeleton 0.00013 0.0045 1.34 197 KEGG MAPK signaling pathway 0.00030 0.0066 1.29 251 KEGG Cell adhesion molecules cams 0.0018 0.035 1.33 122 KEGG ECM receptor interaction 0.0034 0.049 1.36 83 KEGG Wnt signaling pathway 0.0052 0.064 1.27 145 KEGG Hedgehog signaling pathway 0.0057 0.064 1.40 55 KEGG Leukocyte transendothelial migration 0.011 0.10 1.28

UR - https://www.scopus.com/pages/publications/85214473080

U2 - 10.1007/s00401-024-02838-3

DO - 10.1007/s00401-024-02838-3

M3 - Comment/debate/note

C2 - 39747763

AN - SCOPUS:85214473080

SN - 0001-6322

VL - 149

JO - Acta Neuropathologica

JF - Acta Neuropathologica

IS - 1

M1 - 4

ER -

Correction to: Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors (Acta Neuropathologica, (2024), 148, 1, (68), 10.1007/s00401-024-02836-5)

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