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Evaluation of aspects controlling crystallization of nitrofurantoin

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Research › peer-review

1 Citation (Scopus)

Abstract

Nitrofurantoin was crystallized from multiple mixtures of water and organic solvents with and without additives in order to find and identify factors affecting phase obtained in crystallization and provide possible information on crystallization control. Obtained crystals were identified with powder X-ray diffractometry. Crystallization control possibilities were evaluated by using polymer additives and crystallization additives, and also by using quantum chemical calculations to investigate the association of nitrofurantoin and additive molecules and calculate Gibbs energy of association.

Original languageEnglish
Title of host publicationMaterials Science and Applied Chemistry II
EditorsMaris Turks
PublisherTrans Tech Publications Ltd
Pages9-13
Number of pages5
ISBN (Print)9783035714074
DOIs
Publication statusPublished - 2019
Event59th International Scientific Conference of Riga Technical University (RTU) Section of Materials Science and Applied Chemistry, MSAC 2018 - Riga, Latvia
Duration: 26 Oct 2018 → 26 Oct 2018

Publication series

NameKey Engineering Materials
Volume800 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference59th International Scientific Conference of Riga Technical University (RTU) Section of Materials Science and Applied Chemistry, MSAC 2018
Country/TerritoryLatvia
CityRiga
Period26/10/18 → 26/10/18

Keywords

  • Crystallization
  • Crystallization control
  • Hydrates
  • Nitrofurantoin

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