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Micro-Raman scattering and infrared spectra of hemoglobin

  • M. Polakovs*
  • , N. Mironova-Ulmane
  • , N. Kurjane
  • , E. Reinholds
  • , M. Grube
  • *Corresponding author for this work
  • University of Latvia
  • Paula Stradina Clinical University Hospital

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Research › peer-review

8 Citations (Scopus)

Abstract

Confocal micro-Raman and FT-IR spectroscopies have been used for detection of radiation influence of hemoglobin of patients examined by radio-isotopes diagnosis (Tc99m). After irradiation we observed some little changes of the Raman scattering bands which connected with out of plane porphyrine bending vibrations, also we observed additional band due to methemoglobin. Radiation of blood lead to the transition from hemoglobin (Fe2+) to methemoglobin (Fe3+) with a delocalization of iron from porphyrine plane. It was shown that FT-IR spectra indicate the radiation effects on hemoglobin.

Original languageEnglish
Title of host publicationSixth International Conference on Advanced Optical Materials and Devices (AOMD-6)
DOIs
Publication statusPublished - 2008
Event6th International Conference on Advanced Optical Materials and Devices, AOMD-6 - Riga, Latvia
Duration: 24 Aug 2008 → 27 Aug 2008

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7142
ISSN (Print)0277-786X

Conference

Conference6th International Conference on Advanced Optical Materials and Devices, AOMD-6
Country/TerritoryLatvia
CityRiga
Period24/08/08 → 27/08/08

Keywords

  • Blood
  • FT-IR spectroscopy
  • Hemoglobin
  • Raman scattering

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