Numerical optimal control for HIV prevention with dynamic budget allocation

Dmitry Gromov; I. Bulla; O. Silvia Serea; E. O. Romero-Severson

doi:10.1093/imammb/dqx015

Numerical optimal control for HIV prevention with dynamic budget allocation

Dmitry Gromov^*
, I. Bulla
, O. Silvia Serea
, E. O. Romero-Severson

^*Corresponding author for this work

St. Petersburg State University
Walther-Rathenau-Straße 47
Université de Perpignan
Los Alamos National Laboratory

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

Original language	English
Pages (from-to)	469-491
Number of pages	23
Journal	Mathematical Medicine and Biology
Volume	35
Issue number	4
DOIs	https://doi.org/10.1093/imammb/dqx015
Publication status	Published - 5 Dec 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 5 Gender Equality

Keywords

AIDS
HIV
numerical methods
optimal control
pre-exposure prophylaxis
resource allocation
treatment as prevention

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10.1093/imammb/dqx015

Cite this

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title = "Numerical optimal control for HIV prevention with dynamic budget allocation",

abstract = "This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.",

keywords = "AIDS, HIV, numerical methods, optimal control, pre-exposure prophylaxis, resource allocation, treatment as prevention",

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AU - Bulla, I.

AU - Silvia Serea, O.

AU - Romero-Severson, E. O.

PY - 2018/12/5

Y1 - 2018/12/5

N2 - This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

AB - This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

KW - AIDS

KW - HIV

KW - numerical methods

KW - optimal control

KW - pre-exposure prophylaxis

KW - resource allocation

KW - treatment as prevention

UR - https://www.scopus.com/pages/publications/85055349488

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Numerical optimal control for HIV prevention with dynamic budget allocation

Abstract

UN SDGs

Keywords

Access to Document

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