Abstract
[3+2] Cyclocondensation reactions of a series of 1,3- and 2,3-disubstituted 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles with N-ethyl- and N-phenyl-substituted maleimides have been used to obtain the corresponding 6,6-dimethyl-4,4',6'-trioxo-4,5,6,7-3',3'a,4',5',6',6'a-decahydrospiro- [indazole-5,3'-pyrrolo[3,4-c]pyrazoles]. On boiling these compounds in toluene nitrogen is split off and they are converted into 6',6'-dimethyl-2,4,4'-trioxo- 4',5',6',7'-tetrahydro-1'H-spiro[3-azabicyclo-(3.1.0)hexane-6,5'-indazoles].
| Original language | English |
|---|---|
| Pages (from-to) | 545-553 |
| Number of pages | 9 |
| Journal | Chemistry of Heterocyclic Compounds |
| Volume | 45 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2009 |
| Externally published | Yes |
Keywords
- 1,3- and 2,3-substituted 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7- tetrahydroindazoles
- N-ethyl- and N-phenylmaleimides
- [3+2] cycloaddition reactions
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