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Reactions of 1-aryl- and 2,3-diaryl- 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7- tetra- hydroindazoles with N-ethyl- and N-phenyl-substituted maleimides

  • I. Strakova
  • , M. Turks
  • , E. Bizdena
  • , S. Belyakov
  • , A. Tokmakov
  • , A. Strakovs*
  • *Corresponding author for this work
  • Riga Technical University
  • Latvian Institute of Organic Synthesis

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

[3+2] Cyclocondensation reactions of a series of 1,3- and 2,3-disubstituted 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles with N-ethyl- and N-phenyl-substituted maleimides have been used to obtain the corresponding 6,6-dimethyl-4,4',6'-trioxo-4,5,6,7-3',3'a,4',5',6',6'a-decahydrospiro- [indazole-5,3'-pyrrolo[3,4-c]pyrazoles]. On boiling these compounds in toluene nitrogen is split off and they are converted into 6',6'-dimethyl-2,4,4'-trioxo- 4',5',6',7'-tetrahydro-1'H-spiro[3-azabicyclo-(3.1.0)hexane-6,5'-indazoles].

Original languageEnglish
Pages (from-to)545-553
Number of pages9
JournalChemistry of Heterocyclic Compounds
Volume45
Issue number5
DOIs
Publication statusPublished - May 2009
Externally publishedYes

Keywords

  • 1,3- and 2,3-substituted 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7- tetrahydroindazoles
  • N-ethyl- and N-phenylmaleimides
  • [3+2] cycloaddition reactions

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