The effect of probiotics on the genotoxicity of furazolidone

J. Raipulis; M. M. Toma; P. Semjonovs

doi:10.1016/j.ijfoodmicro.2004.11.029

The effect of probiotics on the genotoxicity of furazolidone

J. Raipulis
, M. M. Toma^*
, P. Semjonovs

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T₂₀ (81.9%).

Original language	English
Pages (from-to)	343-347
Number of pages	5
Journal	International Journal of Food Microbiology
Volume	102
Issue number	3
DOIs	https://doi.org/10.1016/j.ijfoodmicro.2004.11.029
Publication status	Published - 25 Jul 2005

Keywords

Antigenotoxicity
Furazolidone
Genotoxicity
Probiotics
SOS chromotest

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10.1016/j.ijfoodmicro.2004.11.029

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title = "The effect of probiotics on the genotoxicity of furazolidone",

abstract = "Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0\%) and for Lactobacillus acidophilus T20 (81.9\%).",

keywords = "Antigenotoxicity, Furazolidone, Genotoxicity, Probiotics, SOS chromotest",

author = "J. Raipulis and Toma, \{M. M.\} and P. Semjonovs",

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AU - Toma, M. M.

AU - Semjonovs, P.

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N2 - Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T20 (81.9%).

AB - Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T20 (81.9%).

KW - Antigenotoxicity

KW - Furazolidone

KW - Genotoxicity

KW - Probiotics

KW - SOS chromotest

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SP - 343

EP - 347

JO - International Journal of Food Microbiology

JF - International Journal of Food Microbiology

IS - 3

ER -

The effect of probiotics on the genotoxicity of furazolidone

Abstract

Keywords

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