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Towards combined multispectral, FLIM and Raman imaging for skin diagnostics

  • University of Latvia
  • Bulgarian Academy of Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Research › peer-review

4 Citations (Scopus)

Abstract

To explore challenges for further improvement of diagnostic performance, a project aimed at development of technology for tri-modal skin imaging by combining multispectral, fluorescence lifetime and Raman band imaging was initiated. In this study, each of the mentioned imaging modalities has been preliminary tested and updated. Four different multispectral imaging devices were tested on color standards. Picosecond laser-excited fluorescence lifetime imaging equipment was examined on ex-vivo skin samples. Finally, a new Raman spectroscopy setup with 785 nm laser was launched and tested on cell cultures and ex-vivo skin. Advantages and specific features of the tri-modal skin imaging are discußed.

Original languageEnglish
Title of host publicationMultimodal Biomedical Imaging XV
EditorsFred S. Azar, Xavier Intes, Qianqian Fang
Place of PublicationBellingham
PublisherSPIE
Pages1-8
Volume11232
ISBN (Electronic)9781510632271
ISBN (Print)978-151063227-1, 9781510632271
DOIs
Publication statusPublished - 2020

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11232
ISSN (Print)1605-7422

OECD Field of Science

  • 2.5 Materials Engineering
  • 1.3 Physical Sciences

Keywords

  • Optical skin diagnostics
  • Multimodal biomedical imaging
  • Fluorescence lifetime
  • Raman spectroscopy

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