TY - JOUR
T1 - Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia
AU - NoDARS ESBL-carrier working group
AU - Ny, Sofia
AU - Kozlov, Roman
AU - Dumpis, Uga
AU - Edquist, Petra
AU - Gröndahl-Yli-Hannuksela, Kirsi
AU - Kling, Anna Maria
AU - Lis, Danuta O.
AU - Lübbert, Christoph
AU - Pomorska-Wesołowska, Monika
AU - Palagin, Ivan
AU - Vilde, Aija
AU - Vuopio, Jaana
AU - Walter, Jan
AU - Wisell, Karin Tegmark
AU - Rantakokko-Jalava, Kaisu
AU - Gunell, Marianne
AU - Rintala, Esa
AU - Marttila, Harri
AU - Kurvinen, Tiina
AU - Lönnqvist, Emilia
AU - Virta, Mari
AU - Kaarto, Anne Mari
AU - Talja, Mikko
AU - Eckmanns, Tim
AU - Sin, Muna Abu
AU - Velasco, Edward
AU - Rodloff, Arne C.
AU - Lempp, Felix Samuel
AU - Lippmann, Norman
AU - Ivanchik, Natali
AU - Dyar, Oliver
AU - Giske, Christian
AU - Brewczyński, Piotr Z.
AU - Horoń, Lidia
AU - Kantele, Anu
AU - Pakkanen, Sari H.
N1 - Publisher Copyright:
© 2018, The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries). The aim was to get indicative data on the prevalence of ESBL-carriage in specific populations in the region. Faecal samples were collected from four study populations and screened on ChromID-ESBL and ChromID-OXA-48 plates. Positive isolates were further characterised phenotypically. Our results show a large variation in carrier prevalence ranging from 1.6% in Latvia to 23.2% in Russia for EP-EC. For the other partner countries, the prevalence of EP-EC were in increasing numbers, 2.3% for Germany, 4.7% for Finland, 6.6% for Sweden, 8.0% for Poland and 8.1% for all partner countries in total. Carriers of EP-KP were identified only in Finland, Russia and Sweden, and the prevalence was < 2% in each of these countries. No carriers of carbapenemase-producing isolates were identified. This is the first study reporting prevalence of carriers (excluding traveller studies) for Finland, Latvia, Poland and Russia. It contributes with important information regarding the prevalence of EP-EC and EP-KP carriage in regions where studies on carriers are limited.
AB - We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries). The aim was to get indicative data on the prevalence of ESBL-carriage in specific populations in the region. Faecal samples were collected from four study populations and screened on ChromID-ESBL and ChromID-OXA-48 plates. Positive isolates were further characterised phenotypically. Our results show a large variation in carrier prevalence ranging from 1.6% in Latvia to 23.2% in Russia for EP-EC. For the other partner countries, the prevalence of EP-EC were in increasing numbers, 2.3% for Germany, 4.7% for Finland, 6.6% for Sweden, 8.0% for Poland and 8.1% for all partner countries in total. Carriers of EP-KP were identified only in Finland, Russia and Sweden, and the prevalence was < 2% in each of these countries. No carriers of carbapenemase-producing isolates were identified. This is the first study reporting prevalence of carriers (excluding traveller studies) for Finland, Latvia, Poland and Russia. It contributes with important information regarding the prevalence of EP-EC and EP-KP carriage in regions where studies on carriers are limited.
KW - Antibiotic resistance
KW - Asymptomatic carriage
KW - E. coli
KW - ESBL
KW - K. pneumoniae Europe and Russia
UR - https://www.scopus.com/pages/publications/85055496406
U2 - 10.1007/s10096-018-3382-8
DO - 10.1007/s10096-018-3382-8
M3 - Article
C2 - 30338465
AN - SCOPUS:85055496406
SN - 0934-9723
VL - 37
SP - 2347
EP - 2354
JO - European Journal of Clinical Microbiology and Infectious Diseases
JF - European Journal of Clinical Microbiology and Infectious Diseases
IS - 12
ER -
3. IAM — Laba Veselība un Labbūtība