Microwave promoted automated synthesis of coumarin library

M. Katkevičs; A. Kontijevskis; I. Mutule; E. Sũna

Microwave promoted automated synthesis of coumarin library

M. Katkevičs^*
, A. Kontijevskis
, I. Mutule
, E. Sũna

^*Šī darba korespondējošais autors

Latvian Institute of Organic Synthesis

Zinātniskās darbības rezultāts: Devums žurnālam › Zinātniskais raksts (žurnālā) › koleģiāli recenzēts

1 Atsauce (Scopus)

Kopsavilkums

A 30-membered library of coumarins has been synthesized in a microwave assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction media. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of purpose-built microwave synthesizer with liquid handling tools rendered automated synthesis of coumarin library feasible.

Oriģinālvaloda	Angļu
Lapas (no-līdz)	200-208
Lapu skaits	9
Žurnāls	Khimiya Geterotsiklicheskikh Soedinenii
Izdevuma numurs	2
Publikācijas statuss	Publicēts - 2007
Ārēji publicēts	Jā

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title = "Microwave promoted automated synthesis of coumarin library",

abstract = "A 30-membered library of coumarins has been synthesized in a microwave assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction media. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of purpose-built microwave synthesizer with liquid handling tools rendered automated synthesis of coumarin library feasible.",

keywords = "Coumarin, Library synthesis, Microwave promoted synthesis",

author = "M. Katkevi{\v c}s and A. Kontijevskis and I. Mutule and E. Sũna",

year = "2007",

language = "English",

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journal = "Khimiya Geterotsiklicheskikh Soedinenii",

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publisher = "Latvian Institute of Organic Synthesis",

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T1 - Microwave promoted automated synthesis of coumarin library

AU - Katkevičs, M.

AU - Kontijevskis, A.

AU - Mutule, I.

AU - Sũna, E.

PY - 2007

Y1 - 2007

N2 - A 30-membered library of coumarins has been synthesized in a microwave assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction media. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of purpose-built microwave synthesizer with liquid handling tools rendered automated synthesis of coumarin library feasible.

AB - A 30-membered library of coumarins has been synthesized in a microwave assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction media. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of purpose-built microwave synthesizer with liquid handling tools rendered automated synthesis of coumarin library feasible.

KW - Coumarin

KW - Library synthesis

KW - Microwave promoted synthesis

UR - https://www.scopus.com/pages/publications/34147219394

M3 - Article

AN - SCOPUS:34147219394

SN - 0132-6244

SP - 200

EP - 208

JO - Khimiya Geterotsiklicheskikh Soedinenii

JF - Khimiya Geterotsiklicheskikh Soedinenii

IS - 2

ER -

Microwave promoted automated synthesis of coumarin library

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