Multispectral and autofluorescence RGB imaging for skin cancer diagnostics

This paper presents the results of statistical clinical data, combining two diagnostic methods. A combination of two skin imaging methods - diffuse reflectance and autofluorescence - has been applied for skin cancer diagnostics. Autofluorescence (AF) and multispectral diffuse reflectance images were acquired by custom made prototype with 405 nm, 526 nm, 663 nm and 964 nm LEDs and RGB CMOS camera. Parameter p' was calculated from diffuse reflectance images under green, red and infrared illumination, AF intensity (I') was calculated from AF images exited at 405nm wavelength. Obtained results show that criterion p' > 1 gives possibility to discriminate melanomas and different kind of keratosis from other lesions, and criterion I' < 0.2 gives the possibility to discriminate melanomas from keratosis.