Numerical optimal control for HIV prevention with dynamic budget allocation

Dmitry Gromov; I. Bulla; O. Silvia Serea; E. O. Romero-Severson

doi:10.1093/imammb/dqx015

Numerical optimal control for HIV prevention with dynamic budget allocation

Dmitry Gromov^*
, I. Bulla
, O. Silvia Serea
, E. O. Romero-Severson

^*Šī darba korespondējošais autors

St. Petersburg State University
Walther-Rathenau-Straße 47
Université de Perpignan
Los Alamos National Laboratory

Zinātniskās darbības rezultāts: Devums žurnālam › Zinātniskais raksts (žurnālā) › koleģiāli recenzēts

14 Atsauces (Scopus)

Kopsavilkums

This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

Oriģinālvaloda	Angļu
Lapas (no-līdz)	469-491
Lapu skaits	23
Žurnāls	Mathematical Medicine and Biology
Sējums	35
Izdevuma numurs	4
DOIs	https://doi.org/10.1093/imammb/dqx015
Publikācijas statuss	Publicēts - 5 dec. 2018
Ārēji publicēts	Jā

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title = "Numerical optimal control for HIV prevention with dynamic budget allocation",

abstract = "This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.",

keywords = "AIDS, HIV, numerical methods, optimal control, pre-exposure prophylaxis, resource allocation, treatment as prevention",

author = "Dmitry Gromov and I. Bulla and \{Silvia Serea\}, O. and Romero-Severson, \{E. O.\}",

year = "2018",

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AU - Gromov, Dmitry

AU - Bulla, I.

AU - Silvia Serea, O.

AU - Romero-Severson, E. O.

PY - 2018/12/5

Y1 - 2018/12/5

N2 - This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

AB - This article is about numerical control of HIV propagation. The contribution of the article is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the developed model to compute optimal control profiles; finally, the computed results are applied to the real problem yielding important and practically relevant results.

KW - AIDS

KW - HIV

KW - numerical methods

KW - optimal control

KW - pre-exposure prophylaxis

KW - resource allocation

KW - treatment as prevention

UR - https://www.scopus.com/pages/publications/85055349488

U2 - 10.1093/imammb/dqx015

DO - 10.1093/imammb/dqx015

M3 - Article

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AN - SCOPUS:85055349488

SN - 1477-8599

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SP - 469

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JF - Mathematical Medicine and Biology

IS - 4

ER -

Numerical optimal control for HIV prevention with dynamic budget allocation

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