The effect of probiotics on the genotoxicity of furazolidone

J. Raipulis; M. M. Toma; P. Semjonovs

doi:10.1016/j.ijfoodmicro.2004.11.029

The effect of probiotics on the genotoxicity of furazolidone

J. Raipulis
, M. M. Toma^*
, P. Semjonovs

^*Šī darba korespondējošais autors

Pētījuma izpildes rezultāts: Devums žurnālam › Zinātniskais raksts (žurnālā) › koleģiāli recenzēts

21 Atsauces (Scopus)

Kopsavilkums

Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T₂₀ (81.9%).

Oriģinālvaloda	Angļu
Lapas (no-līdz)	343-347
Lapu skaits	5
Žurnāls	International Journal of Food Microbiology
Sējums	102
Izdevuma numurs	3
DOIs	https://doi.org/10.1016/j.ijfoodmicro.2004.11.029
Publikācijas statuss	Publicēts - 25 jūl. 2005

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title = "The effect of probiotics on the genotoxicity of furazolidone",

abstract = "Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0\%) and for Lactobacillus acidophilus T20 (81.9\%).",

keywords = "Antigenotoxicity, Furazolidone, Genotoxicity, Probiotics, SOS chromotest",

author = "J. Raipulis and Toma, \{M. M.\} and P. Semjonovs",

year = "2005",

month = jul,

day = "25",

doi = "10.1016/j.ijfoodmicro.2004.11.029",

language = "English",

volume = "102",

pages = "343--347",

journal = "International Journal of Food Microbiology",

issn = "0168-1605",

publisher = "Elsevier B.V.",

number = "3",

}

TY - JOUR

T1 - The effect of probiotics on the genotoxicity of furazolidone

AU - Raipulis, J.

AU - Toma, M. M.

AU - Semjonovs, P.

PY - 2005/7/25

Y1 - 2005/7/25

N2 - Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T20 (81.9%).

AB - Antigenotoxic activity of probiotic bacteria against furazolidone was studied using the short-term bacterial assay SOS chromotest, with Escherichia coli PQ37 as the test organism. The supernatants from probiotic and furazolidone co-incubation exhibited rather strong suppression on SOS induction produced by furazolidone on E. coli PQ 37 (sfiA: lacZ). Genotoxicity inhibition was found for all strains of the examined bacteria belonging to three genera. The highest genotoxicity inhibition was detected for Bifidobacterium lactis Bb-12 (92.0%) and for Lactobacillus acidophilus T20 (81.9%).

KW - Antigenotoxicity

KW - Furazolidone

KW - Genotoxicity

KW - Probiotics

KW - SOS chromotest

UR - https://www.scopus.com/pages/publications/21844459475

U2 - 10.1016/j.ijfoodmicro.2004.11.029

DO - 10.1016/j.ijfoodmicro.2004.11.029

M3 - Article

C2 - 16014301

AN - SCOPUS:21844459475

SN - 0168-1605

VL - 102

SP - 343

EP - 347

JO - International Journal of Food Microbiology

JF - International Journal of Food Microbiology

IS - 3

ER -

The effect of probiotics on the genotoxicity of furazolidone

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